Calsyntenin 3β clstn3β
WebJul 8, 2024 · Recently, another study has shown that Calsyntenin 3β (Clstn3β) mediated the secretion of S100b, which posed a neurotrophic factor, enhancing the sympathetic innervations of BAT and beige iWAT . Consistent with this study, we demonstrated that Adtrp could bind to S100b and mediate the secretion of S100b, which in turn promoted … Webof calsyntenin 3β, and forced expression of S100b in brown adipocytes rescues the defective sympathetic innervation that is caused by ablation of calsyntenin 3β. Our data re veal a mammal-specific mechanism of communication between ... named calsynt enin 3β (CLSTN3β ), promotes the sympathetic inner - vation of both brown and beige ...
Calsyntenin 3β clstn3β
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Web詳細. Calsyntenin 3beta (UniProt: A0A4P8DYG6; also known as Calsyntenin-3β, CLSTN3β) is encoded by the Clstn3 (also known as Clstn3b) gene (Gene ID: 232270) in murine species. CLSTN3β is a mammal-specific that is preferentially expressed in thermogenic adipocytes and is localized in endoplasmic reticulum. Its expression in … WebMoreover, Zeng et al. show that a previously unknown protein, named calsyntenin 3β (CLSTN3β), promotes the sympathetic innervation of both brown and beige adipocytes [91]. CLSTN3β binds to and ...
WebNov 2, 2024 · Similarly, calsyntenin-3β (CLSTN3β) binds to and enhances the expression of neurotrophic factor S100b, which in turn encourages local sympathetic growth and arborization (Zeng et al., 2024). CLSTN3β silencing or upregulation reduces or enhances sympathetic innervation in BAT, respectively, and CLSTN3β ablated subjects on a high … WebMay 1, 2024 · Here we show that a previously unknown, mammal-specific membrane protein, which we have named calsyntenin 3β (CLSTN3β), …
WebJan 29, 2024 · Calsyntenin-3 interacts with both α- and β-neurexins in the regulation of excitatory synaptic innervation in specific Schaffer collateral pathways. Kim H, et al. J …
WebCalsyntenin 3β (CLSTN3β) is a mammal-specific membrane protein that promotes the sympathetic innervation of brown and beige adipocytes by binding to S100b, which in turn acts as a neurotrophic factor to stimulate sympathetic axon growth. CLSTN3β localizes to the endoplasmic reticulum; this interaction enables it to enhance secretion of S100b ...
WebMay 1, 2024 · Europe PMC is an archive of life sciences journal literature. platform black knee high bootsWebSep 25, 2024 · Of interest here, S100b was recently shown to be regulated by a previously unknown adipose-specific calsyntenin 3β (Clstn3β) molecule. Neuronal calsyntenins … platform body trucks for saleWebSep 25, 2024 · Europe PMC is an archive of life sciences journal literature. platform black shoes chunkyWebMay 2, 2024 · 曾等在《自然》杂志发表论文，发现calsyntenin 3β (CLSTN3β)在神经纤维支配褐色脂肪中发挥关键作用，能通过调节生长因子S100b蛋白的分泌影响褐色脂肪产热 … platform black knee bootsWebMoreover, Zeng et al. show that a previously unknown protein, named calsyntenin 3β (CLSTN3β), promotes the sympathetic innervation of both brown and beige adipocytes … platform boat lift costWebDec 7, 2024 · A adipocyte-selective product of the Clstn3 locus (CLSTN3β) present in only placental mammals facilitates the efficient use of stored triglyceride by limiting lipid droplet (LD) expansion, defining a molecular mechanism that regulates LD form and function to facilitate lipid utilization in thermogenic adipocytes. Multilocular adipocytes are a hallmark … pride group in primghar iowaWebMar 7, 2024 · A recent study by Tontonoz and colleagues revealed that calsyntenin-3β (CLSTN3β)—a member of a family of proteins that regulate intracellular trafficking, synaptic function, and neuronal communication —acts to confine lipid droplet-associated proteins averting droplet fusion to maintain the multilocular lipid droplet morphology . pride group inc