Webdrug interactions between other carbapenems and valproic acid (17). In conclusion, due to the rapid decrease level of valproic acid of meropenem and less benefit to increase the dosage of valproic acid to achieve the therapeutic level, the avoidance of co-administration of valproic acid and meropenem in cases when co-administration is necessary. WebFeb 22, 2024 · The interaction of carbapenems and valproic acid (VPA) is significant, of rapid onset, and should be avoided if possible [20]. It leads to decreased serum levels of VPA and may result in loss of ...
Interactions between carbapenems and valproic acid
WebCochrane library using the following keywords: valproate, valproic acid, carbapenem, ertapenem, doripenem, meropenem, imipenem, and valproate drug interaction. In addition, a manual search through ... WebJun 27, 2024 · Valproic acid (2-propylpentanoic acid; VPA) is a branched-chain carboxylic acid introduced as an anti-epileptic drug in 1978 in the United States. It is used to treat … base amarga para unhas
Drug interaction between valproic acid and carbapenems in …
WebValproic acid is normally used to treat seizures, bipolar disorders, and migraines. Physicians are cautioned against prescribing carbapenem antibiotics to these patients, as an interaction can occur between the two drugs, lowering the concentration of VPA in the bloodstream. Usually this would be an unwanted side effect, leaving the patient ... WebFeb 22, 2024 · Combining valproate derivatives with carbapenem antibiotics is associated with a potential drug interaction that decreases serum concentration of valproate and … WebInteractions Enter a drug name and valproic acid All Interactions Sort By: Contraindicated (0) Serious - Use Alternative (19) adagrasib bremelanotide calcium/magnesium/potassium/sodium... svizzera napoli