WebMethods: This is a retrospective cohort study that included patients with Head and Neck Cancers treated with concurrent chemo-radiation with either of the two schedules of Cisplatin using 100 mg/m2 every three weeks or 40 mg/m2 every week. WebCisplatin may cause severe kidney problems, nerve problems, and severe nausea and vomiting. Nerve problems may occur during treatment or weeks after stopping treatment.

Cisplatin 40mg/m2 weekly Head and Neck Regimen

WebAug 8, 2024 · Platelet count < 100 x 103/μL; Hemoglobin level < 9.0 g/dL; Serum creatinine > 1.5 x upper limit of normal (ULN) unless creatinine clearance is ≥ 40 mL/min (measured or calculated using the Cockcroft-Gault formula); Aspartate aminotransferase (AST)/Alanine aminotransferase (ALT): > 3.0 x ULN; WebOct 13, 2024 · Creatinine clearance ≥ 40 ml/min measured by the Cockroft Gault formula Total bilirubin < 1.25 x ULN Aspartate transaminase (AST) and alanine transaminase (ALT) ≤ 2.5 x ULN Performance status of 0, 1 or 2 on the Eastern Cooperative Oncology Group (ECOG) Scale (Appendix A) Age 18 years or older Life expectancy of ≥ 12 weeks Written … crystarium turn ins

Cisplatin 40mg/m2 weekly Head and Neck Regimen

WebApr 10, 2024 · Cisplatin (40 mg/m2) was delivered weekly during external beam radiation therapy and once with brachytherapy. Among 26 eligible patients with para-aortic metastasis or high common iliac involvement, 16 (62%) patients had a complete response for both local and nodal disease. However, the acute and late grade 3/4 toxicity rate was 81% and 40% ... WebMar 1, 2024 · Chemoradiotherapy with weekly cisplatin at a dose of 40 mg/m 2 is widely used as a possible alternative, albeit without sufficient evidence. This clinical trial was … WebA multi-institutional observational study on the effects of three-dimensional radiotherapy and weekly 40-mg/m2 cisplatin on postoperative uterine cervical cancer patients with high-risk prognostic factors crystar ment